Introduction:
The triple quadrupole performance with extremely high sensitivity, recognized performance reliability, and overall system stability can meet your quantitative analysis needs.The Agilent 6400 series triple quadrupole liquid chromatography-mass spectrometry system is suitable for quantitative analysis applications in drug ADME/DMPK research, biomarker validation, clinical research, food testing, forensic science, toxicology, and environmental analysis fields.

selectAgilent 6420、 The 6460, 6470, or 6495 triple quadrupole liquid chromatography-mass spectrometry system achieves very high analysis efficiency, performance, and value for all your analysis needs.

The 6420 system is cost-effective, simple and easy to use, making it a suitable choice for laboratories that require conventional standard quantitative analysis capabilities.

The 6460 system incorporates mature Agilent Jet Stream (AJS) technology to enhance sensitivity and reliability in trace analysis and various challenging applications.

As the stable triple quadrupole system designed by Agilent so far,The 6470 system combines improved ion optical components with detector design to achieve Ak level sensitivity, providing ultra fast analysis and reliable all-weather operation for high-throughput laboratories, improving analysis efficiency.

With breakthroughBased on iFunnel technology, the 6495 system has detection and quantification limits as low as the Ak Zeptomole level within a wide linear dynamic range, making it suitable for demanding applications.

Achieve higher sensitivity and accuracyThe 6495 system adopts Agilent iFunnel technology, a new ion optical system and detector, which can improve ion sampling, transmission and detection effects, achieve higher peak area response, excellent peak area accuracy, and extremely low detection and quantification limits.

Screening, confirmation, and quantificationTriggered Multi Reaction Monitoring (tMRM) combines rapid and sensitive MRM quantitative analysis with the generation of sub ion spectra for spectral library retrieval, compound screening, and confirmation.

Automated compound optimizationThe MassHunter Optimizer software can automatically determine compound multi reaction monitoring (MRM) parameters as well as ion source and iFunnel conditions.

fastMRM acquisition speed and ion polarity switching - Innovative collision cell technology eliminates cross interference, achieving 1 ms MRM dwell time and fast polarity switching, ensuring suitability for UHPLC analysis.

Simplified Method DevelopmentDynamic Multi Reaction Monitoring (dMRM) effectively simplifies method development, allowing for the quantification of thousands of compounds using a single method with higher sensitivity and reproducibility.

Compatible with various types of ion sources- ESI AJS、APCI、APPI、 The multi-mode ion source and innovative HPLC chip technology enable stable and highly sensitive quantitative analysis with only a small sample size.

Functional and user-friendlyThe MassHunter Workstation software greatly improves work efficiency in various aspects such as method optimization, data collection, data processing, and reporting.